O. A. Yanborisova, V. Kolla, S. A. Vikhareva
Feb 1, 1991
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Journal
Pharmaceutical Chemistry Journal
Abstract
Anaigetic and anti-infiam~natory activity was found in 4-(i-phenyi-2-dimethyiaminoformyihydrazino)-8-chioroquinoiine [5]. 2-Hydrazinoquinoline inhibits aminooxidazes [7]. A search was undertaken in the present work for anti-inflammatory and analgetic compounds among quinoiine derivatives containing amide and hydrazine functions the 2-hydrazinocinchoninic acid amides and their substituted derivatives. To achieve this aim, we studied the reactions of 2-chlorocinchoninic acid amides (Ia-m) with hydrazine and its derivatives.