G. Fleet, A. Shaw, S. V. Evans
Nov 5, 1985
Citations
1
Influential Citations
45
Citations
Journal
Journal of The Chemical Society, Chemical Communications
Abstract
1,5-Dideoxy-1,5-imino-L-fucitol (1), synthesised from methyl α-D-glucopyranoside, is a potent competitive inhibitor of the hydrolysis of p-nitrophenyl α-L-fucopyranoside catalysed by α-L-fucosidase (ex. bovine epididymis) causing 50% inhibition of enzymic activity at 2.5 × 10–8M.