E. S. Ibrahim, A. M. Farghaly, H. M. Salama
Dec 6, 1977
Citations
0
Influential Citations
0
Citations
Journal
Die Pharmazie
Abstract
Among the hypotensive drugs are the N-alkyldibenz[c,e]-azepines. A representative of this class is 6-allyl-6,7-dihydro-5H-dibenz[c,e]azepine (azapetine). The present investigation involved the preparation of a new series of N-[6,7-dihydro-5H-dibenz[c,e]azepin-6-yl] acid amides namely; acetamide, benzamide, phehyl acetamide, salicylamide and p-hydroxybenzamide derivatives. Another new series of N-[6,7-dihydro-5H-dibenz[c,e]azepin-6-yl]-N-alkyl (or aryl) thioureas was prepared namely ethyl, isopropyl, butyl, cyclohexyl, benzyl, phenyl and o-tolyl thiourea derivatives. IR spectra of the two series of compounds were investigated.