Kevin J. Wiese, K. Yakushijin, D. Horne
Jul 15, 2002
Citations
1
Influential Citations
45
Citations
Journal
Tetrahedron Letters
Abstract
A short synthesis of the marine sponge alkaloids dibromophakellstatin (1) and dibromoisophakellin (2) is described. The synthesis of 1 centers on a putative biomimetic oxidative cyclization of imidazolone 5. Thermal rearrangement of dibromophakellin (9) in the presence of K2CO3 afforded dibromoisophakellin (2).