Lide Yu, Yiling Zhang, P. Wan
Apr 27, 2021
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Abstract
Dicloxacillin sodium is an antibiotic which is used for the infection of penicillin G resistant Staphylococcus aureus. In addition, Dicloxycillin sodium can be used in the treatment of gram-positive aerobic cocci, and it has the effect of anti-penicillin on a variety of Staphylococcus aureus and Staphylococcus epidermidis. In this article, the synthesis method of Dicloxycillin sodium was established. The structure of the target compound was confirmed by 1H NMR. In addition, the post-process of condensation and salt formation is also provided. Overall, the total yield of 13 steps is about 70.54%.