Tony Y. Zhang, O'toole John Cunningham, J. M. Dunigan
Mar 19, 1998
Citations
0
Influential Citations
26
Citations
Journal
Tetrahedron Letters
Abstract
Abstract Diphenyl cyanomethylenephosphonate (PhO) 2 POCH 2 CN was prepared as a stable crystalline solid in high yield in a single step from acetonitrile, LDA, and (PhO) 2 P(O)Cl. The potassium ylide generated from this compound afforded α,β-unsaturated nitriles upon reacting with aldehydes, with a stereoselectivity of 64–100% favoring the cis -isomer.