J. Aszodi, P. Fauveau, Dominique Melon-Manguer
Apr 15, 2002
Citations
0
Influential Citations
3
Citations
Journal
Tetrahedron Letters
Abstract
Abstract A new diol-carbonyl transposition reaction has been discovered in echinocandin type structures. An α-hydroxy hemiaminal moiety has been shown to undergo a pinacol-type rearrangement in the presence of trimethylsilyl iodide to afford ketone derivatives. Applied to deoxymulundocandin, this transposition led to a useful intermediate for further chemical modification.