A. Endo, A. Yanagisawa, Masanao Abe
May 17, 2002
Citations
3
Influential Citations
202
Citations
Quality indicators
Journal
Journal of the American Chemical Society
Abstract
The total synthesis of ecteinascidin 743 (1), an extremely potent antitumor agent, has been accomplished. The synthesis features Ugi's 4CC reaction, intramolecular Heck reaction, phenol-aldehyde cyclization, and acid-induced intramolecular sulfide formation.