Judith L. Johnson, E. Elslager, L. M. Werbel
Nov 1, 1977
Citations
0
Influential Citations
7
Citations
Journal
Journal of Heterocyclic Chemistry
Abstract
Bromination of 2-dibenzothiophenamine has been shown to afford 1-bromo-2-dibenzothio-phenamine rather than the previously reported 3-isomer. This material was converted to the 1-cyano derivative and cyclized with chloroformamidine hydrochloride to [l]benzothieno-[3,2-f]quinazoline-1,3-diamine. Both this and the corresponding 7,7-dioxide were devoid of antimalarial activity.