A. Kamal, T. Krishnaji, G.B. Ramesh Khanna
Dec 4, 2006
Citations
0
Influential Citations
24
Citations
Journal
Tetrahedron Letters
Abstract
Lipase-mediated kinetic resolution of methyl-3-hydroxy-5-phenylpentanoate and (6E)-ethyl 5-hydroxy-3-oxo-7-phenylhept-6-enoate is described in high enantiomeric excess and good yields. The effect of different lipases in different solvents has been screened using different acylating agents. This protocol has been extended for the preparation of enantiomerically pure biologically important kavalactones.