L. Harwood, S. Tyler, A. S. Anslow
Dec 23, 1997
Citations
0
Influential Citations
11
Citations
Journal
Tetrahedron-asymmetry
Abstract
Abstract (5S)-5-Phenyl-5,6-dihydro-2H-1,4-oxazin-2-one 2 undergoes lewis acidmediated chemo- and diastereoselective nucleophilic addition of Grignard reagents to furnish adducts 3 which can be dismantled to allow ready access to enantiomerically pure (S)-α-amino acids 4.