D. Pflum, H. Wilkinson, G. Tanoury
Mar 1, 2001
Citations
0
Influential Citations
28
Citations
Journal
Organic Process Research & Development
Abstract
Enantiomerically pure cetirizine can be prepared by preparative HPLC separation of cetirizine amide. The amide has an α value of 2.76 (USP resolution of 8.54) using a Chiralpak AD column, and 0.5 wt % of the amide (based on packing material) can be injected per run.