Jogula Srinivas, Yoichi Namito, R. Matsubara
May 9, 2017
Citations
0
Influential Citations
0
Citations
Journal
The Journal of organic chemistry
Abstract
We have accomplished the asymmetric synthesis of (8S,9S,10R,6Z)-trihydroxyoctadec-6-enoic acid in optically pure form and determined the absolute configuration of the natural product on the basis of the stereodetermined chiral building block 7, which was prepared by the catalytic enantioselective allylic oxidation of 4,5-epoxycyclohex-1-ene using an S-configured N,N-bidentate ligand-copper catalyst.