A. Fadel*, Nabil Lahrache
Jan 26, 2007
Citations
0
Influential Citations
19
Citations
Journal
The Journal of organic chemistry
Abstract
Enantiomerically pure (R)-(+)-pipecolic acid was synthesized in four steps and 42% overall yield starting from dihydropyran and (R)-alpha-methylbenzylamine. A general short strategy is also described for preparing (S)-proline (47.5% overall yield) and derivatives.