K. Mori, S. Senda
1985
Citations
0
Influential Citations
44
Citations
Journal
Tetrahedron
Abstract
(2R,5S)-2-Methyl-5-hexanolide and its antipode were synthesized in highly optically pure state (⩾98–99% e.e.) starting from ethyl (S)-lactate and the enantiomers of methyl β-hydroxyisobutyrate. The specific rotations of our samples were [α]D±91.0-93.5° (CHCl3), while the reported values of the samples prepared by resolution or asymmetric synthesis were ±64.5–65.6°.