B. Lamm, R. Simonsson, S. Sundell
1989
Citations
0
Influential Citations
17
Citations
Journal
Tetrahedron Letters
Abstract
Abstract The pure enantiomers of felodipine, 1 , have been synthesized by chromatographic separation of diastereomeric esters with (R)-1-(p-toluenesulfonyl)-3-trityloxypropan-2-ol, 3 , as an easily removable chiral auxiliary. Absolute configurations have been deduced via X-ray crystallography on a (R)-mandelic acid ester, 9B .