C. Greck, F. Ferreira, J. Genêt
Mar 18, 1996
Citations
0
Influential Citations
33
Citations
Journal
Tetrahedron Letters
Abstract
Abstract The first syntheses of enantiomerically pure (2R, 3R) and (2S, 3S) 3-hydroxypipecolic acids 1 and 2 respectively, have been achieved from methyl 7-methyl-3-oxo-6-octenoate. Key steps involved asymmetric hydrogenation and electrophilic amination.