G. Pandey, S. Tiwari, R. Singh
Jun 4, 2001
Citations
0
Influential Citations
21
Citations
Journal
Tetrahedron Letters
Abstract
A short and efficient synthesis of optically pure (+)-N-Boc-azabicyclo[2.2.1]hept-2-one (2), a precursor in the synthesis of natural (−)-epibatidine (1), is reported by the asymmetric desymmetrization of meso-N-methoxycarbonyl-2,3-bis(phenylsulfonyl)-7-azabicyclo[2.2.1]hept-2-ene (3).