Ruipeng Li, Zhenren Liu, Liang Chen
Sep 6, 2018
Citations
0
Influential Citations
3
Citations
Journal
Beilstein Journal of Organic Chemistry
Abstract
In order to prepare eptazocine hydrobromide effectively, a novel, mild and practical asymmetric process was developed starting from 1-methyl-7-methoxy-2-tetralone under the catalysis of N-(p-trifluoromethylbenzyl)cinchonidinium bromide. The reaction conditions were optimized to obtain the product in excellent overall yield and purity.