Jayesh V.Padaliya, M.V.Parsania, A.V.Kalavadia
2013
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Journal
Organic Chemistry: An Indian Journal
Abstract
4-acetanido-2-ethoxy benzoyl hydrazine (2) obtains by reacting hydrazine withmethyl 4-acetamido-2-ethoxybenzoate. Further compound (2)was condensed with different aldehydes. Cyanohydrin which is obtain by addition reaction between different aromatic aldehyde and potassium cyanide in acidicmediumto afforded newa-(4ÂÂÂÂ-acetamido-2ÂÂÂÂ-ethoxybenzoly hydrazino) aryl aceto nitrile derivatives in good yields (65 to 90 %). The structure of newly synthesized compound was confirmed by IR, 1H NMR, Mass spectral studies and elemental analysis. All the synthesized compounds have been screened for antimicrobial activity.