A. Tai, Mei Aburada, Hideyuki Ito
Dec 1, 2014
Citations
0
Influential Citations
8
Citations
Journal
Bioscience, Biotechnology, and Biochemistry
Abstract
A single-step synthesis of 3-O-ethyl-l-ascorbic acid was performed without the induction of protecting groups. Sodium l-ascorbate reacted with ethyl bromide in DMSO to give 3-O-ethylascorbic acid in a yield of 51.0%. 3-O-Ethylascorbic acid enhanced dibutyryl cyclic AMP-induced neurite outgrowth in PC12 cells.