Zhizhen Zhang, Bin Xiao, Qi Chen
Jan 21, 2010
Citations
1
Influential Citations
38
Citations
Journal
Journal of natural products
Abstract
A high-yield synthesis of caffeic acid 3,4-dihydroxyphenethyl ester (1) has been achieved through Knoevenagel condensation of 3,4-dihydroxybenzaldehyde and 3,4-dihydroxyphenethyl monomalonate as the key step. Compound 1 was tested against a 56-cell-line cytotoxicity panel and for its free-radical-scavenging activity in the DPPH test.