B. Takale, N. V. Desai, Afsar Ali Siddiki
Sep 1, 2013
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Journal
Medicinal Chemistry Research
Abstract
The reaction of pyrrole or dibromopyrrole-2-trichloroacetone with various amines results in the series of novel pyrrole-2-carboxamide bearing aromatic heterocycle or aryl or alkyl groups. Synthesized molecules were evaluated for their in vitro antibacterial activities. Most of the compounds exhibited potent activity against both Gram-positive and negative pathogens.