M. Said, K. Abouzid, Ashraf Mouneer
May 1, 2004
Citations
0
Influential Citations
31
Citations
Journal
Archives of Pharmacal Research
Abstract
In this study, a series of 4-amino-5-cyano-3-substituted-2,3-dihydrothiazol-2-thiones(1a-c), as well as their triazolo and triazinopyrimidine derivatives such as 8-substituted-3-benzyl-5-methylthiazolo [5,4-e][1,2,4] triazolo[1,5-c]pyrimidin-2-thiones(4-6, 10) and 3-benzyl-5-methyl thiazolo [5,4-e]pyrimidino[3,4-b][1,2,4]triazin-2-thiones(7a-b) were prepared as potential antimicrobial and antitumor agents. Some of the tested compounds showed promising antimicrobial activity and non of them showed any appreciable antitumor activity.