P. Kate, V. M. Gurame, D. Sirsat
Apr 1, 2020
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Journal
Journal of emerging technologies and innovative research
Abstract
A series of some 2-{(Z)-[(3-Methyl-5-sulfanyl-4H-1,2,4-triazol-4-yl)imino]methyl}-4H-chromen-4-ones were synthesized by reaction of substituted 4-oxo-4H-1-benzopyran-3-carbaldehyde with 4-amino-5-methyl-4H-1,2,4-triazole-3-thiol in acidic medium. The synthesized compounds were characterized by proton NMR, 13C NMR, IR and mass spectroscopy techniques. The products were screened for their antioxidant and anti-inflammatory activities. Compound MP 2 and MP 6 demonstrate excellent antioxidant activity while remaining compounds show moderate activity. Compounds MP 2 and MP 3 demonstrate excellent anti-inflammatory activity while compounds MP 4, MP 6 and MP 8 show moderate activity.