K. Okuma, A. Oba, Risa Kuramoto
Dec 15, 2017
Citations
1
Influential Citations
5
Citations
Journal
European Journal of Organic Chemistry
Abstract
1,4-Dihydrodibenzo[b,h][1,6]naphthyridines were synthesized by the reaction of 2-acetylaminobenzaldehyde with acetophenones in the presence of NaOH. The N-methylation of the dihydrodibenzonaphthyridines with MeI gave 1,1-dimethylammonium iodides. These salts showed UV/vis absorbance maxima at 235 and 418 nm and very weak fluorescence at 530 nm. The fluorescence intensities were enhanced 3-10 times when these salts were treated with double-stranded DNA via intercalation, which enabled the detection of DNA/RNA in PAGE gels.