Wenzhang Xiong, Zhongyan Chen, Yinlin Shao
Mar 3, 2020
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Influential Citations
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Journal
Organic chemistry frontiers
Abstract
A Pd-catalyzed tandem reaction of 2-(cyanomethoxy)chalcones with thiophenes through direct C–H addition and sequential intramolecular conjugate addition/cyclization/aromatization provides a diverse range of 3-aryl-1-(thiophen-2-yl)benzofuro[2,3-c]pyridines. A representative product was assessed as a ratiometric fluorescent probe for Hg2+. This chemistry could also be applied to the synthesis of other fused ring systems.