Y. Kanaoka, Tetsuo Takahashi, H. Nakayama
Nov 25, 1977
Citations
0
Influential Citations
63
Citations
Journal
Chemical & Pharmaceutical Bulletin
Abstract
L-Arginine-4-methylcoumaryl-7-amide 2 and its derivatives, which contain 7-amino-4-methylcoumarin 1 as a key fluorescence amine, were synthesized. The L-antipodes of Nα-benzoyl and Nα-carbobenzoxy derivatives were shown to be the useful fluorogenic substrates for the sensitive determinations of trypsin and papain.