Calum W. Muir, A. Kennedy, Joanna M Redmond
May 1, 2013
Citations
1
Influential Citations
35
Citations
Journal
Organic & biomolecular chemistry
Abstract
4H-Quinolizin-4-ones are a unique class of heterocycle with valuable physicochemical properties and which are emerging as key pharmacophores for a range of biological targets. A tandem Horner-Wadsworth-Emmons olefination/cyclisation method has been developed to allow facile access to substituted 4H-quinolizin-4-ones encoded with a range of functional groups.