Verena Specowius, Franziska Bendrath, Marleen Winterberg
Apr 16, 2012
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Influential Citations
19
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Journal
Advanced Synthesis & Catalysis
Abstract
Functionalized indolizines were prepared by Lewis acid-catalyzed cyclizations of 3-(pyridin-2-yl)-propiolates with enones. This new type of reaction provides a convenient and regioselective approach to ester-substituted indolizine derivatives which are not readily available by other methods. Based on density function theory (DFT) calculations, a mechanism of the reaction has been suggested.