D. Rocha, Kelly Mota, Illana M. C. B. da Silva
May 20, 2014
Citations
0
Influential Citations
22
Citations
Journal
Tetrahedron
Abstract
Abstract Two complementary methodologies involving olefin ring-closing metathesis and Knoevenagel-electrocyclization were utilized for the synthesis of α-xyloidones and fused chromene-1,4-naphthoquinones 5f – n and 6 . The latter methodology was performed under acid catalysis or microwave irradiation allowing the synthesis of α-xyloidones 5f – j in moderate to good yield, which could not be obtained via the Knoevenagel-electrocyclization method. On the other hand, the lawsone bis-alkylation ( C and O ) then RCM olefin enabled the preparation of simple xyloidone 5m – n and the oxepin-1,4-naphthoquinones 6 .