J. Clark, Damian M. Grainger, Alexandra A-C Ehkirch
Feb 21, 2007
Citations
0
Influential Citations
20
Citations
Journal
Organic letters
Abstract
The tetracyclic fused polyether core of the marine natural product hemibrevetoxin B has been prepared in an efficient manner by using a strategy in which ring-closing metathesis (RCM) reactions were employed for ring synthesis. Simultaneous construction of the A and D rings was accomplished by double two-directional RCM of a tetraene. [reaction: see text]