Saskia Louwrier, Antonin Tuynman, H. Hiemstra
Feb 12, 1996
Citations
0
Influential Citations
20
Citations
Journal
Tetrahedron
Abstract
Abstract The syntheses of three bicyclic guanidines as model compounds for the guanidine alkaloid ptilomycalin A are described. The guanidines are prepared from pyrrolidin-2-one via an N-acyliminium ion coupling reaction with silyl enol ethers and a direct guanylation with bis-Boc-thiourea and HgCl2 as the key steps.