A. Hassanabadi, Khatereh Khandan-Barani, J. Saffari
Sep 1, 2016
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Journal
Journal of Chemical Research
Abstract
An efficient synthesis of a series of 4-aryl-1-ethyl-7-methyl-1,9-dihydropyrano[4,3-b]pyrazolo[4,3-e]pyridin-5(4H)-one is reported by condensation of aryl aldehydes, 4-hydroxy-6-methyl-2H-pyran-2-one and 1-ethylpyrazol-5-amine in the presence of 10 mol% molecular I2 in ethanol under reflux conditions through a one-pot reaction. The present method offers several advantages such as use of a metal-free catalyst, being inexpensive, high yielding and environmental acceptability.