A. Chowdhury, Y. Shibata, M. Morita
Sep 1, 2001
Citations
1
Influential Citations
12
Citations
Journal
Journal of Heterocyclic Chemistry
Abstract
Reaction of 2-aminopyrazine 1 with isothiocyanate, isocyanate or dithioketal reagent furnished pteridines 3,4 in good yield. Thioxo compound 3a was chlorinated, methylated and subsequently displaced by amines. A simple one-step synthesis of heterocondensed pteridines 8–13 by reaction of 2-aminopyrazine with various imino thioacetals was described 8–13.