A. Afghan, L. Roohi, M. M. Baradarani
May 1, 2014
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0
Influential Citations
4
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Journal
Journal of Heterocyclic Chemistry
Abstract
Isoquinolin-5-ylhydrazinium chloride and 5-bromoisoquinolin-8-ylhydrazinium chloride were converted via Fischer syntheses with 3-methylbutan-2-one into indolenines, 2,3,3-trimethyl-3H-pyrrolo[2,3-f]isoquinoline and 5-bromo-2,3,3-trimethyl-3H-pyrrolo[3,2-h]isoquinoline , respectively. Exposure of the indolenines to the Vilsmeier reagent produced diformyl compounds and , which reacted with arylhydrazines to give the corresponding pyrazoles and . Reaction of with thiourea gave a pyrimidine-2(1H)-thione or with hydroxylamine hydrochloride, an isoxazole .