V. Teetz, R. Geiger, R. Henning
Apr 9, 1985
Citations
0
Influential Citations
23
Citations
Journal
Arzneimittel-Forschung
Abstract
The convergent, diastereoselective synthesis of 2-[N-[(S)-1-ethoxycarbonyl-3-phenylpropyl]-L-alanyl]-(1S,3S,5S)-2- azabicyclo[3.3.0]octane-3-carboxylic acid (Hoe acid (Hoe 498), a new ACE-inhibitor with improved bioavailability and pharmacokinetics, is described.