V. Horishny, T. Chaban, V. Matiychuk
Jul 1, 2020
Citations
0
Influential Citations
0
Citations
Journal
Russian Journal of General Chemistry
Abstract
The reaction of aromatic and heteroaromatic aldehydes with 3-[2-(4-hydroxyphenyl)ethyl]-2-thioxothiazolidine-4-one was studied. A series of new 5-(het)arylidene-3[2-(4-hydroxyphenyl)ethyl]-2-thioxothiazolidine-4-ones was obtained. For synthesized compounds, antitumor and anti-inflammatory activity was studied. Hit-compounds were identified that exceeded the known comparison drugs in their action.