Liangce Rong, Hongxia Han, Hong Jiang
May 1, 2009
Citations
0
Influential Citations
15
Citations
Journal
Journal of Heterocyclic Chemistry
Abstract
An efficient and convenient multicomponent reaction for the preparation of 4-aryl-2-oxo-2,5-dihydro-1H-indeno[1,2-b]pyridine-3-carbonitrile and 4-aryl-2-oxo-1,2,5,6-tetrahydrobenzo[h]quinoline-3-carbonitrile derivatives by the 2,3-dihydroinden-1-one or 3,4-dihydronaphthalen-1(2H)-one, aromatic aldehydes, and malononitrile in the presence of sodium hydroxide under solvent-free condition is reported. The short reaction time coupled with the simplicity of the reaction procedure makes this method one of the most efficient methods for the synthesis of these classes of compounds. J. Heterocyclic Chem., 46, 465 (2009).