Takeshi Ogawa, Haruki Niwa, Kiyoyuki Yamada
1989
Citations
0
Influential Citations
13
Citations
Journal
Tetrahedron
Abstract
Abstract Indicine N-oxide ( 1 ), a pyrrolizidine alkaloid potentially useful for an anticancer drug was synthesized in the natural form through regioselective coupling of (+)-retronecine ( 2 ) and the protected necic acids 16a and 16b , the latter being efficiently prepared from the optically pure lactone 5 .