F. Ragaini, F. Ventriglia, Mohamed Hagar
May 1, 2009
Citations
0
Influential Citations
45
Citations
Journal
European Journal of Organic Chemistry
Abstract
The addition of Ru3(CO)12, dimethyl carbonate, or both to the reaction mixture improves the selectivity of the palladium/phenanthroline-catalyzed reaction of nitroarenes, arylalkynes, and CO to give 3-arylindoles. When 4-fluorophenylacetylene and nitrobenzene are used as substrates, the indole skeleton of Fluvastatin and other pharmaceutically active compounds is obtained in one step.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)