Peng Xue-wei
2011
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Journal
Chemistry & Bioengineering
Abstract
Using 2-chloronicotinic acid as starting material,2-aminosulfonyl-N,N-dimethylnicotinamide,a key intermediate of herbicide nicosulfuron,is synthesized via several steps after being sulfhydrylated by thiourea.The total yield is 58.1% and this synthetic route has not been reported in domestic.