B. Moritz, Daniel J. Mack, Liuchuan Tong
Mar 10, 2014
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0
Influential Citations
47
Citations
Journal
Angewandte Chemie
Abstract
The total synthesis of sculponeatin N, a bioactive polycyclic diterpene isolated from Isodon sculponeatus, is reported. Key features of the synthesis include diastereoselective Nazarov and ring-closing metathesis reactions, and a highly efficient formation of the bicyclo[3.2.1]octane ring system by a reductive radical cyclization.