J. Hiebl, H. Kollmann, S. Levinson
Nov 5, 1999
Citations
0
Influential Citations
9
Citations
Journal
Tetrahedron Letters
Abstract
Abstract A new and general synthesis of methyl isoquinoline-3-carboxylates is described starting from aromatic 1,2-dialdehydes by reaction with protected phosphonoglycine derivatives. Methyl 1-oxo-1,2-dihydroisoquinoline-3-carboxylates are obtained from 2-formylbenzoate derivatives. This new method allows the preparation of isoquinolines having electron-withdrawing groups on the benzene ring.