M. Adamczyk, Donald D. Johnson, R. E. Reddy
Apr 1, 2000
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0
Influential Citations
3
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Journal
Journal of Labelled Compounds and Radiopharmaceuticals
Abstract
An efficient synthesis of isotopically labeled (+)-deoxypyridinoline (3) was achieved via quaternization of (S,S)(−)-4 with (S)-(−)-iodide (5) and subsequent hydrolysis. The required (S)-(−)-iodide (5) was prepared from a commercially available (S)-5-(tert-butoxy)-4-[tert-butoxycarbonyl)amino]-5-oxopentanoic acid (6) in seven steps and good overall yield. Copyright © 2000 John Wiley & Sons, Ltd.