Zhi-tang Huang, L. Tzai
Jul 1, 1986
Citations
0
Influential Citations
57
Citations
Journal
Chemische Berichte
Abstract
The 4,5-dihydro-2-(methylthio)-1H-imidazoles 1a,b react with active methylene compounds 2a–f to afford the corresponding substituted methyleneimidazolidines 3a–f and 4c–f by elimination of methanethiol. The reaction of compounds 2g–j, which contain a more active carbonyl group, with 1a gives 3g–i by elimination of a methylthio group as well as an acyl group, too. 3a,g–i react with esters of α,β-unsaturated acids to afford the corresponding imidazo[1,2-a]pyridines 5,6, and 7 in an addition and cyclocondensation reaction sequence, but with diethyl azodicarboxylate only to give the addition product 8.