Wu Leifang
2012
Citations
0
Influential Citations
1
Citations
Journal
Journal of Shihezi University
Abstract
Seven novel 3-(2-cinnamamidoethylsulfonyl)-thiazolidine-4-carboxylate derivatives were designed and synthesized in seven steps from taurine,L-cystein methyl ester(ethyl ester) hydrochloride,4-substituted cinnamic acid and other materials. The structures of these seven products were verified by ~1H NMR,~(13)C NMR,MS and IR.All of the target compounds were not reported in the literature and could be used as potential angiotensin converting enzyme(ACE) inhibitors.The method is simple, easy and can be used as a general method to synthesize a series of the thiazolidine-4-carboxylate derivatives.