Y. Nishiyama, Y. Han-ya, S. Yokoshima
Apr 24, 2014
Citations
0
Influential Citations
54
Citations
Journal
Journal of the American Chemical Society
Abstract
The first asymmetric total synthesis of lepenine has been accomplished. The synthesis features a tethered intramolecular Diels-Alder reaction, an intramolecular Mannich reaction, and a Diels-Alder reaction between an ortho-quinone monoketal and ethylene, resulting in stereoselective construction of the unique hexacyclic system.