T. Ohta, N. Sato, Toshihiko Kimura
1988
Citations
0
Influential Citations
22
Citations
Journal
Tetrahedron Letters
Abstract
Abstract (+)-PS-5 p -nitrobenzyl (PNB) ester ( 1a ) has been synthesized from N-Cbz-L-pyroglutamate ( 2a ). The key reactions were the reductive pyrrolidine ring formation from the 5-oxoamino acid derivative ( 3 ) and stereo-differential protonation at C-6 of the dienolate derived from the carbapenam ( 4 ).