Leonard Jurd
1984
Citations
0
Influential Citations
4
Citations
Journal
Journal of Heterocyclic Chemistry
Abstract
2,4-Bis(1,1-dimethyl)-6-[(4-methoxyphenyl)methoxymethyl]phenol (4), prepared by oxidation of 2,4-bis(1,1-dimethylethyl)-6-[(4-methoxyphenyl)methyl]phenol (1) with silver oxide in methanol, reacts with secondary amines in boiling toluene to give Mannich bases (6) related to the biologically active o-benzylphenol. Mannich basis of the isomeric p-benzylphenol (7) were prepared by reaction of amines with the p-quinone methide formed by oxidation of 7.